Profitable companies and non-Profitable Biotech companies (rising stars) have developed innovative drugs for treatment of chronic and non chronic diseases. In the next five years the distinction between mature biotech companies and large global pharma is likely to disappear as investment in R&D and acquisition start delivering and Market Cap match the large global pharma. Dividend and consolidation could be the future drivers and continue to attract long term investors. Optimism prevails around the future of this sector as a whole which was reflected in the unprecedented rally in shares in 2012.
This trend continued in the next five years driven by launch of Innovative drugs catering to unmet needs in Alzheimer’s, HCV, osteoporosis, RA, Psoriasis, MS, Dyslipidemia, Cystic fibrosis, Cancer and orphan diseases. Drug approvals and label expansion of existing portfolio of launched drugs and data from late stage pipeline drugs should maintain the growth momentum and investors interest.
The early part of the previous decade (2010-20) was spent recovering from the big acquisitions made by this sector but followed by the exercising of some restrain for similar large acquisitions as investors wanted to see the returns reflected in the top-line and EPS. However in- licensing of early or mid stage compounds or small acquisitions continued since the Rising Stars kept throwing the bait by taking risks and innovate using novel technology platforms or validating novel targets for treating diseases.
Patent expiry impact was also modest as majority had “not so easy to copy” biologics and other drugs in their portfolio. They, however were not complacent and were not leaving any stones unturned to meet the challenges as well as exploring emerging market opportunities with local partners. Favorable regulatory environment finally saw biosimilar mAbs entry in regulated markets The optimism of biosimilar players is reflected in the maturing pipeline. Para IV Filing from other generic players continues to pour leaving room for surprises and volatility.
Moving forward the sector should see a strategic rise of the digital mindset and further adoption of transformative and augumentative technologies. While mergers & acquisitions can still expect a sharper focus despite being more traditional, external innovation should result in a meaningful shift in culture through innovative and creative partnerships with both new entrants and less traditional companies.
There will be an increasing demand for even more transparency and disclosure and a need for real relationship-driven partnerships will encroach across all sector stakeholders including regulators, patients, advocacy groups and also to outsourcing players critical to the supply chain. Data will be a dominating force behind new revenue models and crucial to understanding and delivering an exceptional patient experience. Pricing will continue to exert much pressure, increasing access to drugs, growth of gene and cell therapies, and uncertain trade policies will further change the dynamics of the market.
Industry News
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In a groundbreaking advancement in urothelial cancer research, scientists have developed a robust predictive model for early recurrence in patients with upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy. This innovative study, recently published in BMC Cancer, promises to transform postoperative management strategies by enabling clinicians to identify high-risk patients with unprecedented accuracy, thereby
- Genetics Behind Slender Anole’s Colorful Dewlapby Bioengineer on April 30, 2025 at 1:16 pm
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- Catalytic Breakdown of Organic-Additive Plasticsby Bioengineer on April 30, 2025 at 1:15 pm
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- The future of NSCLC treatment: what’s in store for the therapeutic space?by Roohi Mariam Peter on April 30, 2025 at 1:01 pm
Here we delve into the different kinds of NSCLC therapies in the running to potentially address late-stage cancer that is often difficult to treat. The post The future of NSCLC treatment: what’s in store for the therapeutic space? appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- 10 Years of Sendai Framework: Boosting Disaster Resilienceby Bioengineer on April 30, 2025 at 12:32 pm
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- Aspirin, NSAIDs Impact Ovarian Cancer Survivalby Bioengineer on April 30, 2025 at 12:11 pm
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- Blocking Hypothalamic Estrogen Drives Lactation Metabolismby Bioengineer on April 30, 2025 at 12:00 pm
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- Reciprocal Actuation Powers Versatile Robotic Limbsby Bioengineer on April 30, 2025 at 11:56 am
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- Single-Cell Insights into Mosaic Focal Cortical Dysplasiaby Bioengineer on April 30, 2025 at 11:35 am
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- Dual IR-Temperature Sensing Reveals Body-Surface Evolutionby Bioengineer on April 30, 2025 at 11:31 am
In a groundbreaking study that promises to transform how we understand and monitor human physiology at the skin interface, researchers have unveiled a novel method leveraging infrared (IR) temperature dual sensing through a single chalcogenide fiber. This pioneering approach opens new frontiers in real-time, non-invasive tracking of dynamic physiological changes on the body surface, a
- Boosting Physical Activity in Middle Age Could Shield Against Alzheimer’s Diseaseby Bioengineer on April 30, 2025 at 11:29 am
A groundbreaking study published in the prestigious journal Alzheimer’s & Dementia has unveiled compelling evidence that increasing physical activity during midlife—specifically between the ages of 45 and 65—may play a crucial role in preventing or delaying the onset of Alzheimer’s disease. This revelation comes from a collaborative effort between the Barcelona Institute for Global Health
- Life’s Crucial 9 Linked to Cancer Survivors’ Mortalityby Bioengineer on April 30, 2025 at 11:09 am
In a groundbreaking cohort study published in BMC Cancer, researchers have unveiled compelling evidence linking a novel cardiovascular health scoring system, Life’s Crucial 9 (LC9), to significantly improved survival outcomes among cancer survivors in the United States. This comprehensive analysis, utilizing data from the National Health and Nutrition Examination Survey (NHANES), offers unprecedented insights into
- Comparing Seismic Hazard: Delineated vs. Smoothed Modelsby Bioengineer on April 30, 2025 at 10:18 am
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- PRDX1 Knockdown Triggers Ferroptosis, Halts Lymphomaby Bioengineer on April 30, 2025 at 9:57 am
In a groundbreaking advancement in cancer research, scientists have uncovered a pivotal mechanism to combat diffuse large B-cell lymphoma (DLBCL), one of the most aggressive and common forms of lymphoma affecting adults worldwide. This study focuses on the role of peroxiredoxin 1 (PRDX1), an antioxidant enzyme, in modulating a specialized form of cell death known
- Six biotech companies leading the charge in hemophilia treatmentby Willow Shah-Neville on April 29, 2025 at 1:00 pm
Discover six hemophilia companies developing new treatments for the genetic bleeding disorder, from gene therapies to RNAi therapies. The post Six biotech companies leading the charge in hemophilia treatment appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- U.S. budget cuts: what is the impact on therapeutic research?by Roohi Mariam Peter on April 28, 2025 at 1:00 pm
We unpack the full scope of the U.S. budget cuts, from canceled clinical trials and stalled drug approvals to mass layoffs and lawsuits. The post U.S. budget cuts: what is the impact on therapeutic research? appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- The past, present, and future of genome sequencingby Jules Adam on April 25, 2025 at 1:00 pm
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- AI in biotech today, and how it will impact the industry tomorrowby Dylan Kissane on April 25, 2025 at 8:00 am
AI is driving innovation across industries, including biotech, but where is its influence felt most and what opportunities for future impact are emerging? The post AI in biotech today, and how it will impact the industry tomorrow appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- 21 UK biotech companies you should know aboutby Willow Shah-Neville on April 24, 2025 at 1:04 pm
Take a closer look at 21 of the top UK biotech companies, as the nation's biotech scene is now one of the most vibrant in Europe. The post 21 UK biotech companies you should know about appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- The emergence of BTK inhibitors in multiple sclerosis treatment: Companies close in on approvalby Willow Shah-Neville on April 23, 2025 at 1:00 pm
Discover why BTK inhibitors have attracted interest for treating multiple sclerosis, as a few late-stage candidates close in on FDA approval. The post The emergence of BTK inhibitors in multiple sclerosis treatment: Companies close in on approval appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Tariffs and trade war: A guide for expanding biotech business internationallyby Jules Adam on April 22, 2025 at 1:42 pm
Find out how you can mitigate the risks on your way to make your biotech company global amidst the tariffs and trade mayhem. The post Tariffs and trade war: A guide for expanding biotech business internationally appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Seven biotechs to watch in the hepatitis B spaceby Roohi Mariam Peter on April 22, 2025 at 8:15 am
Here we take a look at seven biotechs with clinical drug candidates on a quest to win regulatory approval to treat HBV. The post Seven biotechs to watch in the hepatitis B space appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Biomaterials in construction: meet the startups reinventing our buildings by Roohi Mariam Peter on April 17, 2025 at 1:00 pm
We will explore the various biomaterials making a mark in the construction field and how biotechs could potentially transform a carbon-intensive industry. The post Biomaterials in construction: meet the startups reinventing our buildings appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- HIV innovation: Six companies developing new treatments in 2025by Jules Adam on April 16, 2025 at 1:00 pm
Delve into the landscape of biotech companies developing treatments for HIV and find out if we are getting closer to a cure. The post HIV innovation: Six companies developing new treatments in 2025 appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Beyond CRISPR: Brink Therapeutics raises $4 million with engineered recombinasesby Jules Adam on April 16, 2025 at 6:30 am
Learn about Brink Tx as it raises $4 million to go beyond CRISPR with engineered recombinases in CAR T therapy. The post Beyond CRISPR: Brink Therapeutics raises $4 million with engineered recombinases appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Protecting Your Drug Patent in Global Markets: Strategies and Challengesby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 27, 2025 at 9:19 am
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- Effective Strategies for Generic Drug Price Settingby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 25, 2025 at 9:17 am
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- Optimizing the Generic Drug Supply Chain: Strategies for Successby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 24, 2025 at 11:56 pm
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