Profitable companies and non-Profitable Biotech companies (rising stars) have developed innovative drugs for treatment of chronic and non chronic diseases. In the next five years the distinction between mature biotech companies and large global pharma is likely to disappear as investment in R&D and acquisition start delivering and Market Cap match the large global pharma. Dividend and consolidation could be the future drivers and continue to attract long term investors. Optimism prevails around the future of this sector as a whole which was reflected in the unprecedented rally in shares in 2012.
This trend continued in the next five years driven by launch of Innovative drugs catering to unmet needs in Alzheimer’s, HCV, osteoporosis, RA, Psoriasis, MS, Dyslipidemia, Cystic fibrosis, Cancer and orphan diseases. Drug approvals and label expansion of existing portfolio of launched drugs and data from late stage pipeline drugs should maintain the growth momentum and investors interest.
The early part of the previous decade (2010-20) was spent recovering from the big acquisitions made by this sector but followed by the exercising of some restrain for similar large acquisitions as investors wanted to see the returns reflected in the top-line and EPS. However in- licensing of early or mid stage compounds or small acquisitions continued since the Rising Stars kept throwing the bait by taking risks and innovate using novel technology platforms or validating novel targets for treating diseases.
Patent expiry impact was also modest as majority had “not so easy to copy” biologics and other drugs in their portfolio. They, however were not complacent and were not leaving any stones unturned to meet the challenges as well as exploring emerging market opportunities with local partners. Favorable regulatory environment finally saw biosimilar mAbs entry in regulated markets The optimism of biosimilar players is reflected in the maturing pipeline. Para IV Filing from other generic players continues to pour leaving room for surprises and volatility.
Moving forward the sector should see a strategic rise of the digital mindset and further adoption of transformative and augumentative technologies. While mergers & acquisitions can still expect a sharper focus despite being more traditional, external innovation should result in a meaningful shift in culture through innovative and creative partnerships with both new entrants and less traditional companies.
There will be an increasing demand for even more transparency and disclosure and a need for real relationship-driven partnerships will encroach across all sector stakeholders including regulators, patients, advocacy groups and also to outsourcing players critical to the supply chain. Data will be a dominating force behind new revenue models and crucial to understanding and delivering an exceptional patient experience. Pricing will continue to exert much pressure, increasing access to drugs, growth of gene and cell therapies, and uncertain trade policies will further change the dynamics of the market.
Industry News
- Depression drug trials are failing—and placebos are to blameby Roohi Mariam Peter on March 21, 2025 at 2:00 pm
In this article, we examine recent clinical trial failures and discuss potential pathways forward for antidepressant drug research. The post Depression drug trials are failing—and placebos are to blame appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Almost 50% of Depression Cases May Be Resistant to Treatment, Study Findsby Bioengineer on March 21, 2025 at 10:39 am
In a recent groundbreaking study, researchers have unveiled alarming statistics regarding treatment-resistant depression (TRD), indicating that nearly half of individuals diagnosed with depression do not respond adequately to traditional antidepressant therapies. Published in the prestigious British Journal of Psychiatry, this research sheds light on the increasing challenge of finding effective treatments for one of the
- Deadly Bacteria Evolve Antimicrobial Production, Eliminating Competitorsby Bioengineer on March 21, 2025 at 10:21 am
A groundbreaking study led by the University of Pittsburgh School of Medicine has unveiled a concerning evolutionary leap among vancomycin-resistant Enterococcus faecium (VREfm), a notorious pathogen prevalent in healthcare settings. Researchers have identified significant genomic changes in this bacterium, allowing it to weaponize antimicrobial genetic tools, thereby establishing dominance over its relatives. This discovery stems
- New Device Facilitates Direct Communication Between Multiple Quantum Processorsby Bioengineer on March 21, 2025 at 10:19 am
Quantum computing stands on the precipice of revolutionizing the way we approach complex problem-solving. Unlike classical computers, which process information in a linear fashion through bits that are either in a state of 0 or 1, quantum computers leverage the unique properties of quantum mechanics. These systems utilize qubits, which can exist in a superposition
- Are mitochondrial therapeutics about to go mainstream?by Dylan Kissane on March 21, 2025 at 9:00 am
Listen to our talk with Klaus Dugi, CEO of Vandria, about mitochondrial therapeutics and longevity The post Are mitochondrial therapeutics about to go mainstream? appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Revolutionary Nanotechnology Enhances Crop Yields in Arid Regionsby Bioengineer on March 21, 2025 at 6:58 am
In a groundbreaking study conducted at the King Abdullah University of Science and Technology (KAUST), researchers have unveiled a remarkable advancement in agricultural technology designed for arid regions. The study focuses on the development of a novel nanoplastic and biodegradable mulch that serves the dual purpose of enhancing greenhouse efficiency through passive cooling and promoting
- Revolutionary Ultrafine Bubble Showers Show Promise in Treating Atopic Dermatitisby Bioengineer on March 21, 2025 at 5:44 am
Ultrafine Bubble Showers Show Promise Against Atopic Dermatitis in Mice In an intriguing advancement in dermatological research, a team from Osaka Metropolitan University has unveiled findings suggesting that ultrafine bubble showers may significantly alleviate symptoms of atopic dermatitis in mice. This condition, characterized by inflamed and itchy skin, is often exacerbated by environmental irritants and
- Engineered Yeast Enhances D-Lactic Acid Production: A Greener Recipe for Sustainabilityby Bioengineer on March 21, 2025 at 2:19 am
Researchers at Osaka Metropolitan University have made groundbreaking advancements in the production of D-lactic acid through the optimization of yeast fermentation processes. Their innovative approach focuses on genetically engineering the yeast species Komagataella phaffii, enabling it to efficiently convert methanol into D-lactic acid, a critical building block for various biodegradable plastics and pharmaceuticals. This research
- Leveraging Computational Methods to Discover Natural Products Against SARS-CoV-2by Bioengineer on March 21, 2025 at 1:48 am
The urgent quest for effective therapeutic agents against SARS-CoV-2 has taken on renewed significance in the wake of the COVID-19 pandemic. Despite widespread vaccination efforts that have been successful in controlling the virus’s spread, the persistent emergence of new variants continues to pose challenges to global health strategies. This situation has necessitated the exploration of
- Nearly 50% of Children with Complicated Appendicitis Recover from Surgery at Homeby Bioengineer on March 21, 2025 at 1:23 am
Recent research has unveiled a transformative approach to post-operative care for children undergoing surgery for complicated appendicitis, highlighting the potential benefits of home recovery. A significant study conducted by the Murdoch Children’s Research Institute (MCRI) and published in the Journal of Pediatric Surgery demonstrates that nearly half of these young patients can safely recuperate at
- Sensory T-Shirt Gathers Patient Data, Leading to Reduced Postoperative Hospital Staysby Bioengineer on March 21, 2025 at 1:11 am
A revolutionary development in the field of urology could hasten recovery times for patients undergoing cancer surgeries. Researchers have introduced a novel t-shirt that continuously monitors vital signs of individuals who have had robot-assisted urological surgery. The implications of this technology could significantly reduce the duration of hospital stays, thereby allowing patients the comfort of
- Men Who Forego Prostate Cancer Screening Face Increased Health Risksby Bioengineer on March 21, 2025 at 1:10 am
Men who systematically evade prostate cancer screenings are significantly increasing their risk of dying from this prevalent disease, according to groundbreaking research that delineates a new, high-risk demographic. This insight arises from a comprehensive analysis derived from the European Randomized Study of Screening for Prostate Cancer (ERSPC), recognized as the world’s most extensive investigation into
- Study Reveals Diversity and Inclusion Challenges Within Sleep Research Society Membershipby Bioengineer on March 21, 2025 at 12:34 am
The issue of diversity, equity, and inclusion in professional organizations has garnered increasing attention over the past few years, and a recent study from the Sleep Research Society sheds light on the prevailing disparities among its members. This comprehensive research, conducted in December 2024, highlights the experiences of historically minoritized individuals within the organization, revealing
- New Research Highlights the Crucial Role of Genomic Screening in Assessing Disease Riskby Bioengineer on March 21, 2025 at 12:16 am
Genetic screening is rapidly becoming a crucial area of focus in modern medicine, offering insights into individuals’ risks for various diseases that have long remained hidden. A prime example of this advancement is Geisinger’s MyCode Community Health Initiative, which has been the subject of extensive research to evaluate its effectiveness in identifying genetic predispositions among
- DNAformer: The Intersection of Nature and Artificial Intelligenceby Bioengineer on March 21, 2025 at 12:06 am
Researchers at the Technion-Israel Institute of Technology are making waves in the field of data storage by developing a breakthrough method for DNA-based data retrieval. This innovative approach harnesses artificial intelligence to significantly speed up the process of accessing data stored in DNA, achieving retrieval times that are three orders of magnitude faster than current
- Registration for TCT 2025 Now Available!by Bioengineer on March 21, 2025 at 12:04 am
The Cardiovascular Research Foundation (CRF) is set to host the highly anticipated Transcatheter Cardiovascular Therapeutics (TCT) 2025 conference, beginning on October 25 and continuing through to October 28, 2025. This premier educational symposium stands out as the leading global platform dedicated to advancing the field of interventional cardiovascular medicine. Scheduled to take place at the
- AI meets biotech: Bullfrog AI’s CEO on the TechBio boomby Jules Adam on March 20, 2025 at 2:00 pm
Find out about how TechBios are changing the industry by leveraging AI and partnering with biotech in our interview with Bullfrog AI's CEO. The post AI meets biotech: Bullfrog AI’s CEO on the TechBio boom appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Breast cancer treatments heat up: Five therapies poised to transform patient outcomesby Willow Shah-Neville on March 19, 2025 at 2:25 pm
Find out more about the overall breast cancer treatment landscape, as biotech companies make progress with different approaches. The post Breast cancer treatments heat up: Five therapies poised to transform patient outcomes appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Cancer vaccines: 11 biotechs to keep an eye out forby Roohi Mariam Peter on March 18, 2025 at 2:00 pm
As various biotechs across the world specialize in the production of cancer vaccines, here are 11 companies making progress in the field. The post Cancer vaccines: 11 biotechs to keep an eye out for appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- How biotechs are using AI to rescue failed drugsby Willow Shah-Neville on March 17, 2025 at 2:00 pm
Discover how biotech companies like Ignota Labs and BioXcel Therapeutics are using AI to rescue failed drugs. The post How biotechs are using AI to rescue failed drugs appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Can GLP-1 agonists help treat addiction?by Willow Shah-Neville on March 14, 2025 at 2:00 pm
Discover how researchers have been exploring the potential of GLP-1 drugs for treating addiction disorders. The post Can GLP-1 agonists help treat addiction? appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Fighting Alzheimer’s with innovative stem cell therapiesby Dylan Kissane on March 14, 2025 at 9:00 am
This week, we talk with Christopher Duma about his career in neurosurgery, the impetus for launching his biotech, and the promise of stem cell therapy in Alzheimer's. The post Fighting Alzheimer’s with innovative stem cell therapies appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Nine biotechs thriving in Seattle in 2025by Roohi Mariam Peter on March 13, 2025 at 2:00 pm
In this article, let us take a look at some of the major biotech companies in Seattle that are contributing to the biotech industry at large. The post Nine biotechs thriving in Seattle in 2025 appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Checkpoint inhibitors in cancer: breakthroughs, setbacks, and what’s nextby Roohi Mariam Peter on March 12, 2025 at 2:19 pm
Checkpoint inhibitors are drugs that harness the immune system to destroy cancer cells. Let us review what’s been going on in the field. The post Checkpoint inhibitors in cancer: breakthroughs, setbacks, and what’s next appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- The gender gap in clinical trials: Why women are still underrepresentedby Jules Adam on March 11, 2025 at 2:00 pm
Find out what led biotech to a situation where women are underrepresented in clinical trials and how the industry is correcting it. The post The gender gap in clinical trials: Why women are still underrepresented appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- 23andMe: the collapse of a genomics giantby Roohi Mariam Peter on March 10, 2025 at 2:00 pm
23andMe was once worth $6 billion and is now a penny stock. Layoffs, data breaches, and mass resignations plagued the genomics giant. How did it all unfold? The post 23andMe: the collapse of a genomics giant appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
- Protecting Your Drug Patent in Global Markets: Strategies and Challengesby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 27, 2025 at 9:19 am
Navigating the Complex World of Global Drug Patents: Strategies and Challenges Ahead As a pharmaceutical professional, you know how crucial it is to protect your innovative drug patents in the global market. With the rise of international trade and the... Source
- Drafting Drug Patent Applications for Biologic Drugsby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 26, 2025 at 11:45 am
The Complex World of Biologic Drugs: Navigating Patent Applications As a biotech professional, you're likely no stranger to the intricacies of developing life-saving treatments. But when it comes to biologic drugs, the process can be particularly chall... Source
- Successfully Patenting Drug Combinations: Strategies and Challengesby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 26, 2025 at 9:57 am
Unlocking the Power of Combination Therapies: Strategies for Successful Patenting As a pharmaceutical professional, you know that combination therapies have revolutionized the treatment of complex diseases. By pairing two or more active ingredients, yo... Source
- Effective Strategies for Generic Drug Price Settingby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 25, 2025 at 9:17 am
The Secret to Setting the Right Price for Your Generic Medications As a generic drug manufacturer, you're constantly looking for ways to stay ahead of the competition and bring affordable medications to market. But have you ever wondered how to set the... Source
- Optimizing the Generic Drug Supply Chain: Strategies for Successby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 24, 2025 at 11:56 pm
Unlocking Efficiency in the Generic Drug Supply Chain As the pharmaceutical industry continues to evolve, the generic drug supply chain has become a critical component of ensuring timely and affordable access to life-saving medications. However, naviga... Source
- FDA Updates: What Do the Latest Changes Mean for Generic Drug Approval?by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 24, 2025 at 8:55 pm
Breaking News: FDA Updates - What Do the Latest Changes Mean for Generic Drug Approval? As a healthcare professional or a business leader in the pharmaceutical industry, you're likely aware of the complex landscape surrounding generic drug approval. Re... Source
- Regulatory Challenges in the Latin American Generic Drug Marketby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 24, 2025 at 4:10 pm
Breaking Down Barriers: Navigating Regulatory Challenges in Latin America's Generic Drug Market As the demand for affordable generic medications continues to grow, Latin America has emerged as a critical region for pharmaceutical companies looking to e... Source
- Analyzing the cost-effectiveness of biosimilars in different healthcare systemsby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 23, 2025 at 11:27 am
The Future of Affordable Healthcare: Can Biosimilars Deliver? As healthcare professionals, we're constantly on the lookout for innovative solutions to improve patient outcomes while reducing costs. One promising approach is the use of biosimilars – bio... Source
- How to Achieve High-Quality Standards in Generic Drugsby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 20, 2025 at 11:21 am
Ensuring the Highest Quality in Generic Medications: A Crucial Step in Healthcare As the global demand for affordable healthcare continues to rise, generic medications have become a vital lifeline for millions of people worldwide. However, with the inc... Source
- The Role of Quality Assurance in Generic Drugsby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 19, 2025 at 11:07 am
The Unseen Heroes of Generic Medicines: The Crucial Role of Quality Assurance As we navigate the complex world of pharmaceuticals, it's easy to overlook the unsung heroes behind the scenes. But today, I want to shine a spotlight on the Quality Assuranc... Source
- DrugChatter: Can lurbinectedin treat ovarian cancer?by DrugChatter on February 19, 2025 at 6:44 am
Can Lurbinectedin Treat Ovarian Cancer? A Comprehensive Review Ovarian cancer is a devastating disease that affects thousands... https://www.Drugchatter.com/chat/25460/can-lurbinectedin-treat-ovarian-cancer/ Source
- Regulatory considerations for biosimilar clinical efficacy trialsby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 18, 2025 at 3:27 pm
Unlocking the Potential of Biosimilars: Navigating Regulatory Considerations for Clinical Efficacy Trials As the pharmaceutical industry continues to evolve, biosimilars have emerged as a game-changer in the quest for affordable and accessible treatmen... Source
- The basics of drug patent searchingby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 18, 2025 at 10:38 am
Unlock the Secrets of Drug Patent Searching: A Beginner's Guide As a professional in the pharmaceutical industry, staying ahead of the curve is crucial. One of the most critical aspects of this is understanding the world of drug patents. But have you e... Source
- Navigating the Generic Drug Approval Process: A Comprehensive Guideby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 17, 2025 at 10:33 am
Unlocking the Path to Generic Medication Approval: A Step-by-Step Guide As a healthcare professional or a business leader in the pharmaceutical industry, you're likely aware of the complex landscape surrounding generic medication approval. With the eve... Source
- Strategies for successful biosimilar-to-biosimilar switchingby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 16, 2025 at 4:04 pm
The Future of Biosimilars: Switching Strategies for Success As the biosimilar market continues to grow, one question on everyone's mind is: how can we make the most of this opportunity? One strategy that's gaining traction is biosimilar-to-biosimilar s... Source
- Study Reveals Key Predictors of Early Patent Challenges for FDA-Approved Drugsby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 14, 2025 at 11:40 am
The Hidden Factors Behind FDA-Approved Drugs' Patent Challenges As a healthcare professional or a pharmaceutical industry expert, you're likely no stranger to the complex world of drug patents. But have you ever wondered what sets some FDA-approved dru... Source
- The Role of Partnerships in Generic Drug Developmentby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 13, 2025 at 9:12 am
Breaking Down Barriers: The Power of Partnerships in Generic Drug Development As the pharmaceutical industry continues to evolve, one thing is clear: collaboration is key. In the world of generic drug development, partnerships are playing an increasing... Source
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- How to Manage Generic Drug Development Timelines: Strategies for Successby Insights: DrugPatentWatch - Find Your Next Blockbuster on February 12, 2025 at 9:10 am
The Art of Timing: Mastering Generic Drug Development Timelines As a seasoned professional in the pharmaceutical industry, you know that navigating the complex landscape of generic drug development can be a daunting task. One of the most critical facto... Source
- DrugChatter: How does lipitor affect white wine?by DrugChatter on February 11, 2025 at 4:56 pm
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