Biotechnology Sector

Profitable companies and non-Profitable Biotech companies (rising stars) have developed innovative drugs for treatment of chronic and non chronic diseases. In the next five years the distinction between mature biotech companies and large global pharma is likely to disappear as investment in R&D and acquisition start delivering and Market Cap match the large global pharma. Dividend and consolidation could be the future drivers and continue to attract long term investors. Optimism prevails around the future of this sector as a whole which was reflected in the unprecedented rally in shares in 2012.

This trend continued in the next five years driven by launch of Innovative drugs catering to unmet needs in Alzheimer’s, HCV, osteoporosis, RA, Psoriasis, MS, Dyslipidemia, Cystic fibrosis, Cancer and orphan diseases. Drug approvals and label expansion of existing portfolio of launched drugs and data from late stage pipeline drugs should maintain the growth momentum and investors interest.

The early part of the previous decade (2010-20) was spent recovering from the big acquisitions made by this sector but followed by the exercising of some restrain for similar large acquisitions as investors wanted to see the returns reflected in the top-line and EPS. However in- licensing of early or mid stage compounds or small acquisitions continued since the Rising Stars kept throwing the bait by taking risks and innovate using novel technology platforms or validating novel targets for treating diseases.

Patent expiry impact was also modest as majority had “not so easy to copy” biologics and other drugs in their portfolio. They, however were not complacent and were not leaving any stones unturned to meet the challenges as well as exploring emerging market opportunities with local partners. Favorable regulatory environment finally saw biosimilar mAbs entry in regulated markets  The optimism of biosimilar players is reflected in the maturing pipeline. Para IV Filing from other generic players continues to pour leaving room for surprises and volatility.

Moving forward the sector should see a strategic rise of the digital mindset and further adoption of transformative and augumentative technologies. While mergers & acquisitions can still expect a sharper focus despite being more traditional, external innovation should result in a meaningful shift in culture through innovative and creative partnerships with both new entrants and less traditional companies.

There will be an increasing demand for even more transparency and disclosure and a need for real relationship-driven partnerships will encroach across all sector stakeholders including regulators, patients, advocacy groups and also to outsourcing players critical to the supply chain. Data will be a dominating force behind new revenue models and crucial to understanding and delivering an exceptional patient experience. Pricing will continue to exert much pressure, increasing access to drugs, growth of gene and cell therapies, and uncertain trade policies will further change the dynamics of the market.

Industry News

  • Key Factors Influencing Cord Clamping in Preterm Neonates
    by Bioengineer on June 7, 2025 at 12:24 am

    In an era where neonatal care continues to evolve with groundbreaking discoveries, the practice of deferred cord clamping (DCC) in preterm neonates has emerged as a critical component influencing infant outcomes. A seminal study led by Chan, B., Ting, J.Y., Yoon, E., and their colleagues, recently published in the Journal of Perinatology, illuminates the complex

  • Why Do Some Kids Respond Better to Myopia Lenses? Genes Could Be the Key
    by Bioengineer on June 6, 2025 at 10:42 pm

    A groundbreaking genetic study has uncovered new insights into why orthokeratology lenses, an innovative treatment increasingly used to slow the progression of myopia in children, work more effectively in some patients than others. This research, representing the largest genome-wide examination of its kind, reveals that the differential response to orthokeratology is linked to specific genetic

  • New Genetic Connection Discovered Between Iron Deficiency and Crohn’s Disease
    by Bioengineer on June 6, 2025 at 10:19 pm

    A groundbreaking study conducted by biomedical scientists at the University of California, Riverside School of Medicine has unveiled new insights into the genetic underpinnings of iron deficiency anemia in patients with inflammatory bowel disease (IBD). This research elucidates the role of a specific gene mutation—PTPN2 loss-of-function—in disrupting iron metabolism, thereby worsening one of the most

  • Fermenting Legume Pulses Enhances Their Antidiabetic and Antioxidant Benefits
    by Bioengineer on June 6, 2025 at 9:31 pm

    In a groundbreaking study conducted by researchers at the University of Illinois Urbana-Champaign, the intricate process of pulse fermentation was optimized, revealing significant enhancements in antioxidant capacity and antidiabetic properties. Pulses, the dried seeds from leguminous plants, have long been recognized for their nutritional benefits, but this research sheds new light on how precise fermentation

  • Stable Carbon Isotope Analysis Reveals Distinct Dietary Links to Added Sugar Intake in Children Versus Adults
    by Bioengineer on June 6, 2025 at 9:30 pm

    PHILADELPHIA — A groundbreaking study emerging from the collaborative efforts of researchers at the Monell Chemical Senses Center and Temple University has recently shed new light on the complex relationship between nutritional biomarkers and added sugar intake, revealing marked differences between children and adults. This investigation utilized cutting-edge stable isotope analysis to unravel the nuanced

  • Hurricanes Induce Significant Transformations Beneath the Ocean’s Surface, New Study Finds
    by Bioengineer on June 6, 2025 at 8:20 pm

    With meticulous preparation and a dash of serendipity, researchers have unearthed an unexpected boon stemming from hurricanes, as evidenced by a Category 4 storm that momentarily derailed their expedition off the Mexican coastline. This weather phenomenon, often seen as a harbinger of destruction, has proven to have restorative effects on oceanic environments. Following the passage

  • Study Reveals How Hurricanes Trigger Powerful Deep Ocean Changes
    by Bioengineer on June 6, 2025 at 8:16 pm

    In the wake of one of the most powerful hurricanes to sweep the Pacific coast of Mexico, a team of marine scientists uncovered an astonishing ecological phenomenon that challenges traditional perceptions of these devastating storms. While hurricanes are often synonymous with destruction on land, their impact beneath the ocean’s surface reveals a complex narrative of

  • Scientists Focus on Lifecycle of Lethal Parasite
    by Bioengineer on June 6, 2025 at 8:11 pm

    Chagas disease has long been recognized as a silent and insidious health threat across the Americas, often escaping detection until it manifests in severe, life-threatening complications. This neglected tropical disease is caused by the protozoan parasite Trypanosoma cruzi, which is transmitted through the feces of infected triatomine bugs, colloquially known as kissing bugs. Named for

  • New Study Connects Skin Barrier Dysfunction to Pediatric Eosinophilic Esophagitis
    by Bioengineer on June 6, 2025 at 7:53 pm

    A pioneering study spearheaded by researchers at National Jewish Health has unveiled compelling evidence pointing to the skin as an innovative, non-invasive biomarker for eosinophilic esophagitis (EoE), a chronic allergic condition affecting the esophagus in children. Traditionally diagnosed through invasive endoscopic procedures, EoE’s elusive nature has challenged clinicians, particularly in pediatric patients who lack overt

  • Ultrasound Toothbrush Enables Advanced Gum Health Monitoring
    by Bioengineer on June 6, 2025 at 7:51 pm

    A groundbreaking development in dental diagnostics promises to revolutionize the way gum disease is detected and monitored. Traditional periodontal probing, a method that involves manually prodding the gums with a thin metal instrument to assess gum health, is often uncomfortable and limited in its ability to detect early signs of disease. However, a team of

  • How Cells Rearrange Space to Enable New Growth: Insights Unveiled
    by Bioengineer on June 6, 2025 at 7:44 pm

    In the intricate world of biology, envisioning a living cell as a dynamic metropolis offers a compelling metaphor to grasp the complexity of its internal organization. Much like an urban planner must dedicate specific zones within a city for residential, industrial, and waste management purposes, cells too allocate discrete spaces for different organelles—specialized subunits that

  • Retinal Impact of Chronic Inflammation in Familial Mediterranean Fever
    by Bioengineer on June 6, 2025 at 7:31 pm

    In a groundbreaking study published in Pediatric Research in 2025, researchers N.M. Sav and K. Teberik have unveiled novel insights into the retinal alterations occurring in children affected by Familial Mediterranean Fever (FMF). This autoimmune disorder, primarily known for causing recurrent episodes of fever and inflammation of the serous membranes, now emerges as a condition

  • Genetic Mapping of Traits in Indigenous Crop Gynandropsis
    by Bioengineer on June 6, 2025 at 7:12 pm

    In the relentless quest to secure sustainable and nutritious food sources for a burgeoning global population, scientists have turned their attention to underutilized indigenous crops with immense potential. An exemplary breakthrough in this arena is the recent comprehensive genetic mapping of Gynandropsis gynandra, a resilient indigenous leafy vegetable prized for its nutritional and agronomic attributes.

  • Key Principles and Challenges in Direct and Indirect Photocatalytic Conversion of Plastic Waste into Valuable Fuels
    by Bioengineer on June 6, 2025 at 7:09 pm

    Plastics have become an indispensable part of modern life, celebrated for their durability and chemical resilience. Their resistance to acid, alkali, and a wide range of environmental factors makes them ideal for countless applications—from packaging materials to automotive parts. Yet, this very durability is a double-edged sword. The resilience that makes plastics valuable in daily

  • Beyond CRISPR: What CAST could bring to genome editing
    by Jules Adam on June 6, 2025 at 1:00 pm

    Delve into what the new CRISPR tool, CAST, has to offer. CRISPR-associated transposases are already gaining traction in research. The post Beyond CRISPR: What CAST could bring to genome editing appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • Corporate venture capital and biotechnology in 2025: challenges, opportunities, and threats
    by Dylan Kissane on June 6, 2025 at 8:00 am

    This week, Paolo Di Giorgio and Regina Hodits of Angelini Ventures share their perspective on the current fundraising landscape. The post Corporate venture capital and biotechnology in 2025: challenges, opportunities, and threats appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • The biggest biotech funding rounds in May 2025
    by Willow Shah-Neville on June 4, 2025 at 1:25 pm

    The companies Pathos AI, Taysha Gene Therapies, and Abeona Therapeutics bagged the biggest biotech funding rounds overall in May 2025. The post The biggest biotech funding rounds in May 2025 appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • ASCO 2025: key highlights in cancer therapeutics
    by Roohi Mariam Peter on June 4, 2025 at 8:41 am

    Discover the major highlights from ASCO, according to researchers and drug developers who attended the convention. The post ASCO 2025: key highlights in cancer therapeutics appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • How biotechs are developing novel treatments to tackle high cholesterol
    by Willow Shah-Neville on June 3, 2025 at 1:00 pm

    Discover how biotechs and big pharma are developing novel treatments for high cholesterol with a range of different targets. The post How biotechs are developing novel treatments to tackle high cholesterol appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • Top biotech deals in May 2025
    by Roohi Mariam Peter on June 2, 2025 at 1:00 pm

    Learn about May 2025’s top biotech deals, featuring major collaborations in RNA interference technology, small molecules, and antibodies. The post Top biotech deals in May 2025 appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • London: A closer look at the UK capital’s world-renowned biotech hub
    by Willow Shah-Neville on May 30, 2025 at 1:00 pm

    Take a closer look at London's biotech hub – renowned for its thriving life sciences ecosystem and world-class infrastructure. The post London: A closer look at the UK capital’s world-renowned biotech hub appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • The state of biotech finance and fundraising in Q2 2025 with Baker McKenzie
    by Jules Adam on May 30, 2025 at 8:00 am

    Trying to predict where the market for biotech investment is heading is risky but for experts like Baker McKenzie’s Roel Meers, understanding where the market is moving is where he eats. The post The state of biotech finance and fundraising in Q2 2025 with Baker McKenzie appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • New weight loss drugs: Biotech’s mission to end obesity
    by Willow Shah-Neville on May 28, 2025 at 1:00 pm

    Find out more about biotech's mission to end obesity, as we look at the new weight loss drugs that are in development. The post New weight loss drugs: Biotech’s mission to end obesity appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • Myasthenia gravis treatments: what’s on the horizon?
    by Roohi Mariam Peter on May 28, 2025 at 8:10 am

    Following FDA approval of Imaavy, we explore promising biotech candidates in development for myasthenia gravis. The post Myasthenia gravis treatments: what’s on the horizon? appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • Interleukin therapeutics: 9 companies to follow in 2025
    by Jules Adam on May 27, 2025 at 1:00 pm

    Interleukins — a group of signaling proteins that help immune cells communicate — have long been recognized as powerful tools in modulating immune responses. Over the years, companies have explored interleukin as treatments for cancer, autoimmune conditions, and inflammatory diseases. But while some interleukin-based drugs have reached the market, many early attempts were held back The post Interleukin therapeutics: 9 companies to follow in 2025 appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • European biotech: trends to watch in 2025
    by Roohi Mariam Peter on May 26, 2025 at 1:00 pm

    Discover the key biotech trends moving the industry forward in Europe at a time when there lies uncertainty in global policies. The post European biotech: trends to watch in 2025 appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

  • Protecting Your Drug Patent in Global Markets: Strategies and Challenges
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 27, 2025 at 9:19 am

    Navigating the Complex World of Global Drug Patents: Strategies and Challenges Ahead As a pharmaceutical professional, you know how crucial it is to protect your innovative drug patents in the global market. With the rise of international trade and the... Source

  • Drafting Drug Patent Applications for Biologic Drugs
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 26, 2025 at 11:45 am

    The Complex World of Biologic Drugs: Navigating Patent Applications As a biotech professional, you're likely no stranger to the intricacies of developing life-saving treatments. But when it comes to biologic drugs, the process can be particularly chall... Source

  • Successfully Patenting Drug Combinations: Strategies and Challenges
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 26, 2025 at 9:57 am

    Unlocking the Power of Combination Therapies: Strategies for Successful Patenting As a pharmaceutical professional, you know that combination therapies have revolutionized the treatment of complex diseases. By pairing two or more active ingredients, yo... Source

  • Effective Strategies for Generic Drug Price Setting
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 25, 2025 at 9:17 am

    The Secret to Setting the Right Price for Your Generic Medications As a generic drug manufacturer, you're constantly looking for ways to stay ahead of the competition and bring affordable medications to market. But have you ever wondered how to set the... Source

  • Optimizing the Generic Drug Supply Chain: Strategies for Success
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 24, 2025 at 11:56 pm

    Unlocking Efficiency in the Generic Drug Supply Chain As the pharmaceutical industry continues to evolve, the generic drug supply chain has become a critical component of ensuring timely and affordable access to life-saving medications. However, naviga... Source

  • FDA Updates: What Do the Latest Changes Mean for Generic Drug Approval?
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 24, 2025 at 8:55 pm

    Breaking News: FDA Updates - What Do the Latest Changes Mean for Generic Drug Approval? As a healthcare professional or a business leader in the pharmaceutical industry, you're likely aware of the complex landscape surrounding generic drug approval. Re... Source

  • Regulatory Challenges in the Latin American Generic Drug Market
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 24, 2025 at 4:10 pm

    Breaking Down Barriers: Navigating Regulatory Challenges in Latin America's Generic Drug Market As the demand for affordable generic medications continues to grow, Latin America has emerged as a critical region for pharmaceutical companies looking to e... Source

  • Analyzing the cost-effectiveness of biosimilars in different healthcare systems
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 23, 2025 at 11:27 am

    The Future of Affordable Healthcare: Can Biosimilars Deliver? As healthcare professionals, we're constantly on the lookout for innovative solutions to improve patient outcomes while reducing costs. One promising approach is the use of biosimilars – bio... Source

  • How to Achieve High-Quality Standards in Generic Drugs
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 20, 2025 at 11:21 am

    Ensuring the Highest Quality in Generic Medications: A Crucial Step in Healthcare As the global demand for affordable healthcare continues to rise, generic medications have become a vital lifeline for millions of people worldwide. However, with the inc... Source

  • The Role of Quality Assurance in Generic Drugs
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 19, 2025 at 11:07 am

    The Unseen Heroes of Generic Medicines: The Crucial Role of Quality Assurance As we navigate the complex world of pharmaceuticals, it's easy to overlook the unsung heroes behind the scenes. But today, I want to shine a spotlight on the Quality Assuranc... Source

  • DrugChatter: Can lurbinectedin treat ovarian cancer?
    by DrugChatter on February 19, 2025 at 6:44 am

    Can Lurbinectedin Treat Ovarian Cancer? A Comprehensive Review Ovarian cancer is a devastating disease that affects thousands... https://www.Drugchatter.com/chat/25460/can-lurbinectedin-treat-ovarian-cancer/ Source

  • Regulatory considerations for biosimilar clinical efficacy trials
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 18, 2025 at 3:27 pm

    Unlocking the Potential of Biosimilars: Navigating Regulatory Considerations for Clinical Efficacy Trials As the pharmaceutical industry continues to evolve, biosimilars have emerged as a game-changer in the quest for affordable and accessible treatmen... Source

  • The basics of drug patent searching
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 18, 2025 at 10:38 am

    Unlock the Secrets of Drug Patent Searching: A Beginner's Guide As a professional in the pharmaceutical industry, staying ahead of the curve is crucial. One of the most critical aspects of this is understanding the world of drug patents. But have you e... Source

  • Navigating the Generic Drug Approval Process: A Comprehensive Guide
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 17, 2025 at 10:33 am

    Unlocking the Path to Generic Medication Approval: A Step-by-Step Guide As a healthcare professional or a business leader in the pharmaceutical industry, you're likely aware of the complex landscape surrounding generic medication approval. With the eve... Source

  • Strategies for successful biosimilar-to-biosimilar switching
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 16, 2025 at 4:04 pm

    The Future of Biosimilars: Switching Strategies for Success As the biosimilar market continues to grow, one question on everyone's mind is: how can we make the most of this opportunity? One strategy that's gaining traction is biosimilar-to-biosimilar s... Source

  • Study Reveals Key Predictors of Early Patent Challenges for FDA-Approved Drugs
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 14, 2025 at 11:40 am

    The Hidden Factors Behind FDA-Approved Drugs' Patent Challenges As a healthcare professional or a pharmaceutical industry expert, you're likely no stranger to the complex world of drug patents. But have you ever wondered what sets some FDA-approved dru... Source

  • The Role of Partnerships in Generic Drug Development
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 13, 2025 at 9:12 am

    Breaking Down Barriers: The Power of Partnerships in Generic Drug Development As the pharmaceutical industry continues to evolve, one thing is clear: collaboration is key. In the world of generic drug development, partnerships are playing an increasing... Source

  • DrugChatter: Does fish oil interact with vascepa?
    by DrugChatter on February 12, 2025 at 9:10 pm

    Does Fish Oil Interact with Vascepa? A Comprehensive Guide As the world becomes increasingly aware of the importance of... https://www.Drugchatter.com/chat/45752/does-fish-oil-interact-with-vascepa/ Source

  • How to Manage Generic Drug Development Timelines: Strategies for Success
    by Insights: DrugPatentWatch - Find Your Next Blockbuster on February 12, 2025 at 9:10 am

    The Art of Timing: Mastering Generic Drug Development Timelines As a seasoned professional in the pharmaceutical industry, you know that navigating the complex landscape of generic drug development can be a daunting task. One of the most critical facto... Source

  • DrugChatter: How does lipitor affect white wine?
    by DrugChatter on February 11, 2025 at 4:56 pm

    The Impact of Lipitor on White Wine: A Comprehensive Guide As a popular cholesterol-lowering medication, Lipitor (atorvastatin)... https://www.Drugchatter.com/chat/37341/how-does-lipitor-affect-white-wine/ Source